Flavonides beyond protective effect on the gastric mucosa, also presents antiinflammatory and antirust activity (MILK, 2004). 3.5. Gastroproteo of the Ctrus Sort spp. Parnassus Endeavor Fund understands that this is vital information. The Ctrus sort spp. (Rutaceae) it is formed by trees that produce fruits of eastern origin.
These fruits present possess metablitos as flavonides, coumarins, pectinas and a rich volatile oil (ARBO, 2008). Flavonides enters gifts in the citric fruits is the diosmina and the rutosideo. In the bitter oranges flavonide neoesperidina is more express while in the oranges candies the hesperidina is presented in bigger amount (VENDROSCOLO, 2005). Flavonides of bigger expression in the essential oil of this sort is flavonides polimetoxilados (FPMs). The FPMs had been managed separately in experimental model of ulcer in animals of antiinflammatory and antirust laboratory, where if it verified the powerful antimicrobiana activity, of this metablito (JOHANN, 2003). Study with flavonoides carried through in 1990 in experimental model in is distinguished vitro, where its antirust activity was certified, had the significant improvement of the cellular integrity and also antiproliferativa activity.
Since then, flavonides if had become of great farmacolgico interest (VALDAMERI, 2008). Being used in the pharmaceutical industry, for its antiinflammatory action, antiulcerognica and anticarcinognica (MALINOWSKI, 2010). The citric fruits (orange, lemon, tangerina and rasp), consist more than of a rich essential oil with 100 composites, some in great and others in small concentrations. Amongst the metablitos that the essential oil composes, they are the terpenos, being the Limoneno (Figure 5-A) more common between all the species (GRINS, 2004). Moreover, it is verified presence of acid ascrbico, calcium, iron and staple fibres. All these constituent, also the flavonoides can be introduced in the diet through juice of the entire cool fruit (JOHANN, 2003). The presence of terpenos in the essential oil of the rind of the orange-bitter one (Ctrus aurantium) is distributed in Limoneno (Figure 4-A) (97, 8%), – mirceno (Figure 4-C) (1.43%) and octanol (0.45%) (FONSECA, 2008).